Hotspots in Framemaker 12, will the work once I create a PDF from the Document, and if so how do I make it happen?

We are using Framemaker 12, and there is a need to create hotspots withing troubleshooting flowcharts that are contained in it, our biggest question is what is the easiest way to make this work, and will the hotspot carry over into a PDF document once we create it.

Thanks,
David